B. gutters
In graphic novels, the white space between and around panels is called the gutter. The gutter is the space where two panels meet. It's important because it allows the reader to visually separate scenes or moments, creating a pause or transition between different parts of the story. This space can also influence pacing and the flow of the narrative.
Frames refer to the borders around each individual panel in the graphic novel. They contain the artwork or scenes but are not the space between the panels.
Layouts refer to the overall arrangement of panels on a page. While they determine how the story is visually structured, they do not specifically refer to the white space between panels.
Captions are text boxes in a graphic novel that provide narrative information, usually placed within or outside panels. They are not related to the white space between panels.
Therefore, B. gutters is the correct answer.